Gut microbiota variations in patients diagnosed with major depressive disorder-A systematic review

This 2015 article reviewed the bidirectional relationship between the gut microbiota and the brain [also termed the microbiota-gut-brain (MGB) axis] using articles taken from the Medline database, and discussed how it contributes to the pathogenesis of certain disorders that may involve brain inflammation. Various afferent or efferent pathways were discovered to be involved in the […]

Major depressive disorder (MDD), being a complicated condition in nature, affects 280 million individuals globally and is a primary cause of disability. Numerous environmental variables, including medicines, nutrition, and microorganisms, have a role in the pathophysiology of depression disorders. The host immune system, genetics, and epigenetics are some of the contributors to the intricate underlying […]