Gut microbiota and bipolar disorder: a review of mechanisms and potential targets for adjunctive therapy

In this review, Gondalia et al. (2019) discuss various comorbid conditions linked with bipolar disorder — such as inflammation, irritable bowel disease, and antibiotic induced mania — which indicate possible involvement of the gut microbiota. Although there is a clear interaction between psychiatry and gastrointestinal health, it has not been well researched thus far. The authors explore the relationships between bipolar disorder, inflammation, and the gut microbiome while discussing the potential of dietary, probiotic, and prebiotic interventions as adjuvant therapies for managing mood disorders. [NPID: mood disorders, psychiatric disorders, gut microbiota, microbiome, inflammation, bipolar disorder, irritable bowel disease, antibiotic induced mania, probiotic, prebiotic]

Year: 2019

Reference: Gondalia, S., Parkinson, L., Stough, C., & Scholey, A. (2019). Gut microbiota and bipolar disorder: a review of mechanisms and potential targets for adjunctive therapy. Psychopharmacology, 236(5), 1433–1443. https://doi.org/10.1007/s00213-019-05248-6