Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial

Shift work is oftentimes overlooked concerning nutritional and lifestyle interventions, despite the role it has been demonstrated to play in raising the odds of cardiometabolic pathologies. In this randomized control trial by Manoogian et al. (2022), the authors investigated the impact of time-restricted eating (TRE) on a sample of 137 shift workers (firefighters, 23-59 years of age, 9% females, 24-hour shifts) for a total of 12 weeks. In the course of the experiment, the participants practiced a 10-hour TRE and had their quality of life (Short form health survey SF-36) and metabolic parameters monitored (serum lipids, glycated hemoglobin [HbA1C], diastolic blood pressure). Participants in the TRE group (n = 70) significantly reduced their eating window to around 11.13 hours per day compared to the Standard of Care (SOC, controls, n = 65) group (13.35 hours) and scored higher on SF-36, indicating an enhanced quality of life. In addition, participants in the TRE group showed several metabolic improvements, including reductions in HbA1C, very-low-density lipoprotein (VLDL) particle size, and diastolic blood pressure, conferring an overall reduction in cardiovascular risk compared to the SOC group. The authors conclude that TRE is a beneficial dietary intervention for shift workers that can decrease cardiometabolic risk factors. [NPID: TRE, time restricted eating, circadian, diabetes, firefighters, hypertension, intermittent fasting, quality of life, shift work, sleep]

Year: 2022

Reference: Manoogian, E., Zadourian, A., Lo, H. C., Gutierrez, N. R., Shoghi, A., Rosander, A., Pazargadi, A., Ormiston, C. K., Wang, X., Sui, J., Hou, Z., Fleischer, J. G., Golshan, S., Taub, P. R., & Panda, S. (2022). Feasibility of time-restricted eating and impacts on cardiometabolic health in 24-h shift workers: The Healthy Heroes randomized control trial. Cell metabolism, 34(10), 1442–1456.e7. https://doi.org/10.1016/j.cmet.2022.08.018