Effects of Gladiolus dalenii on the stress-induced behavioral, neurochemical, and reproductive changes in rats (animal)

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Antidepressant-like effects of penta-acetyl geniposide in chronic unpredictable mild stress-induced depression rat model: Involvement of inhibiting neuroinflammation in prefrontal cortex and regulating hypothalamic-pituitaryadrenal axis (animal)

Cai et al. (2020) report their findings on the antidepressant-like effects of penta-acetyl geniposide ((Ac)5GP, a derivative of geniposide (a major active component of Gardenia jasminoides Ellis). While the rats were under chronic unpredictable mild stress (CUMS), (Ac)5GP treatment seemed to alleviate the depression-like behaviors induced by CUMS. Moreover, the elevations in interleukins (IL-1β, IL-6) […]

Acute ingestion of rosemary water: Evidence of cognitive and cerebrovascular effects in healthy adults

In this 2018 study, 80 healthy adults were randomized to drink either 250 mL of rosemary water or plain mineral water, before completing a series of cognitive tasks and being examined on alertness and fatigue. Hemoglobin levels (total, oxygenated and deoxygenated) were also taken at baseline and throughout the cognitive testing procedure. The results indicated […]