Effect of nutritional interventions on the psychological symptoms of premenstrual syndrome in women of reproductive age: A systematic review of randomized controlled trials

Almost half of all women in the world who are of reproductive age suffer from premenstrual syndrome (PMS), which can impair their ability to function, lower their quality of life, and reduce their productivity at work. Although there are medical therapies available, women tend to look for alternative remedies potentially due to insufficient proof of efficacy and worries about adverse effects. Nevertheless, there is still a dearth of comprehensive studies on how dietary and nutritional therapies affect PMS. This systematic review by Robinson et al. (2024) aims to look at how dietary therapies affect PMS-related psychological symptoms. Five internet databases, including randomized controlled trials (RCTs) published in English up until October 2022, were searched by researchers. Nutritional therapies aimed at women of reproductive age were included in eligible studies, and psychological effects associated with PMS were assessed. Using the Cochrane Risk of Bias 2 methodology and article screening software, three impartial reviewers went through the publications, extracted data, and evaluated the likelihood of bias. 32 publications covering 31 RCTs with 3254 individuals between the ages of 15 and 50 were included in the review, which was narratively evaluated. There was just one study with a low bias risk. Treatments with zinc, calcium, and vitamin B6 have repeatedly shown a considerable favorable impact on psychological symptoms associated with PMS. Nevertheless, there was insufficient data to support the effectiveness of vitamin B1, whole-grain carbs, vitamin D, magnesium, dietary fatty acids, soy multivitamin supplementation, isoflavones, or diets specifically tailored for PMS. Even though there is some evidence that nutritional interventions can help with PMS psychological symptoms, the authors recommend conducting further studies using standardized protocols, bias reduction measures, intention-to-treat analyses, and more transparent reporting to establish firm nutritional recommendations for improving PMS psychological outcomes. [NPID: Diet, nutritional supplements, premenstrual dysphoric disorder, premenstrual syndrome, psychological health]

Year: 2024

Reference: Robinson, J., Ferreira, A., Iacovou, M., & Kellow, N. J. (2024). Effect of nutritional interventions on the psychological symptoms of premenstrual syndrome in women of reproductive age: A systematic review of randomized controlled trials. Nutrition Reviews, nuae043. https://doi.org/10.1093/nutrit/nuae043