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Dietary total antioxidant capacity is inversely associated with depression, anxiety and some oxidative stress biomarkers in postmenopausal women: A cross-sectional study
Since oxidative stress has been implicated in the development of mental disorders, and postmenopausal women are at higher risk of these disorders, Abshirini et al. (2019) aimed to assess the association between dietary total antioxidant capacity (DTAC) and depression, stress and anxiety, and also oxidative stress biomarkers, among a group of postmenopausal women. A total of 175 postmenopausal women took part in the study, who were examined on dietary intake [food frequency questionnaire (FFQ)], and mental health [Depression Anxiety Stress Scale (DASS-42)]. The participants’ dietary and serum total antioxidant capacity (TAC), malondialdehyde (MDA), oxidized-LDL, and superoxide dismutase (SOD) concentrations were also taken. The results showed subjects in the highest tertiles of DTAC had significantly lower MDA levels in the blood (p-value<0.001), and also, serum TAC level was significantly higher in those at the second terile of DTAC (p-value = 0.04). In addition, DTAC was discovered to be inversely and independently related to depression and anxiety scores, although no significant correlation was identified with stress score. These findings signify dietary total antioxidant capacity (DTAC) may be used for developing effective dietary measures for reducing depression and anxiety in postmenopausal women. [NPID: menopause, perimenopause, premenopause, female, women, hormone health, hormone therapy, mental disorders, antioxidants, depression, stress, anxiety]
Year: 2019
