Determining the association between Fibromyalgia, the gut microbiome and its biomarkers: a systematic review

This 2020 systematic review conducted a search for published original research on the gastrointestinal microbiota and its biomarkers in adult fibromyalgia sufferers, and summarised its findings. From 4771 studies, 11 met the inclusion criteria and were separated into four main groups: papers reporting Helicobacter pylori; other gut bacterial markers; metabolomics and other biomarkers, which included intestinal permeability and small intestinal bacterial overgrowth. The results indicated the gut microbiota may play a role in fibromyalgia within the emerging field of the gut-musculoskeletal axis and suggested there is a limited amount of quality research in this area. Erdrich et. al (2020) call for more studies on the relationship between the gut microbiota, gut dysfunction and fibromyalgia. [NPID: pain, gastrointestinal microbiota, intestinal permeability, fibromyalgia, gut-musculoskeletal, gut microbiome, gut dysfunction, gut-brain axis]

Year: 2020

Reference: Erdrich, S., Hawrelak, J. A., Myers, S. P., & Harnett, J. E. (2020). Determining the association between fibromyalgia, the gut microbiome and its biomarkers: A systematic review. BMC musculoskeletal disorders, 21(1), 181. https://doi.org/10.1186/s12891-020-03201-9