Dectin-1 signaling on colonic γδ T cells promotes psychosocial stress responses

In this study by Yadav et al. (2022), the authors investigated the mechanisms linking Multiple Sclerosis (MS) with gastrointestinal inflammation and derangements of the gut microbiome. Humanized transgenic (Tg) HLA-DR2a and human T cell receptor (TCR) specific for myelin basic protein peptide (MBP87-99)/HLA-DR2a were examined for signs of gastrointestinal inflammation (immune cell infiltration) during the […]

The severity of alcohol use disorders (AUDs) has recently been connected to microbiome changes, suggesting that the gut microbiome may play a role in the development of AUDs. The act of consuming an excessive amount of alcohol quickly is known as binge drinking. Binge drinking is frequently seen in the critical adolescent growth stage. In […]