Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial

Related Studies

The efficacy, safety, and tolerability of probiotics on depression: clinical results from an open-label pilot study

Current evidence points to the positive impact of probiotics on improving mood and anxiety symptoms via influencing the gut-brain axis. However, the impact of probiotics on Major Depressive Disorder (MDD) patients who are not on treatment is unknown. In this open-label pilot study by Wallace & Milev (2021), the authors investigated the impact of probiotic […]

Multispecies probiotic administration reduces emotional salience and improves mood in subjects with moderate depression: a randomised, double-blind, placebo-controlled study

Although probiotics have been proposed to have antidepressant effects, their impact on emotional processing—an underlying factor in mood disorders—remains unclear. In this randomized, double-blind, placebo-controlled trial by Baião et al. (2023), 71 individuals with depression participated to assess the effects of a 4-week daily intake of a multispecies probiotic compared to a placebo. Researchers evaluated […]