Biomolecules of Fermented Tropical Fruits and Fermenting Microbes as Regulators of Human Hair Loss, Hair Quality, and Scalp Microbiota

Secondary metabolites from plants (such as polyphenols, terpenes, and alkaloids) along with microbial products from fermented tropical fruits are highly effective in enhancing skin and hair health, offering benefits like wound healing, anti-inflammatory effects, and hair growth promotion. Specifically, caffeine has been recognized for its ability to stimulate hair growth. A clinical trial examined the effectiveness of hair care products containing fermented papaya, fermented mangosteen, and caffeine. These products were tested on 154 participants with certain types of hair loss over a period of three months. The evaluation involved both subjective assessments by dermatologists and objective measurements using trichomicroscopy. Results indicated that these products not only reduced hair loss but also improved hair density, thickness, and follicle structure when compared to placebo and caffeine-only products. Furthermore, they helped normalize scalp microbiota, increase ATP levels in hair follicles, and reduce lipid peroxidation in the scalp, indicating overall improvement in hair and scalp health.

Year: 2023

Reference: Mayer, W., Weibel, M., De Luca, C., Ibragimova, G., Trakhtman, I., Kharaeva, Z., Chandler, D. L., & Korkina, L. (2023). Biomolecules of Fermented Tropical Fruits and Fermenting Microbes as Regulators of Human Hair Loss, Hair Quality, and Scalp Microbiota. Biomolecules, 13(4), 699. https://doi.org/10.3390/biom13040699