Benefits of Curcumin in brain disorders

This 2019 paper is focused on curcumin, a component of the spice turmeric and a widely used ingredient in food recipes. Curcumin is well recognized for its strong anti-inflammatory, antioxidant, anti-cancer, and antimicrobial characteristics. In addition, curcumin is used in diabetes, arthritis, and several hepatic, renal, and cardiovascular diseases. In this review, curcumin is examined on its potential use in neurological diseases such as Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Huntington’s disease, prions disease, stroke, Down’s syndrome, autism, Amyotrophic lateral sclerosis, anxiety, depression, and aging. Recent studies have suggested that curcumin can perhaps prevent or delay the onset of neurodegenerative diseases. This article also discusses the recent progress that has been made to improve the therapeutic efficacy of the curcumin/curcuma formulation, and to ensure safe and effective drug delivery despite low bioavailability and toxicity reports. As well as summarizing the ongoing clinical trials on curcumin for various neurodegenerative diseases, this review showcases the patent details of curcuma/curcumin in India.
[NPID: India, Indian, turmeric, curcumin, herb, spice, inflammation, antioxidant, Alzheimer’s, Parkinson’s, MS, multiple sclerosis, Huntington’s, Prions, Down’s, autism, anxiety, depression, aging]

Year: 2019

Reference: Bhat, A., Mahalakshmi, A. M., Ray, B., Tuladhar, S., Hediyal, T. A., Manthiannem, E… Sakharkar, M. K. (2019). Benefits of curcumin in brain disorders. BioFactors (Oxford, England), 45(5), 666–689. https://doi.org/10.1002/biof.1533

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