Associations of dietary trans fatty acid intake with depressive symptoms in midlife women

The purpose of this 2020 study was to determine the possible link between eating trans fatty acids and having depressive symptoms among midlife women. The data used for study was taken from the Study of Women’s Health Across the Nation (SWAN). The 3095 women included were aged 42 to 52 years. The analysis models indicated that higher trans fatty acid intake was associated with greater scores in the depression assessment (Center for Epidemiological Studies-Depression scores). This relationship was noted in both the linear and logistic regression models. But stratified analysis results showed that trans fatty acid intake was not significantly connected with depressive symptoms in early perimenopausal women (undergoing the transitional period before menopause). According to the sensitivity analyses, the correlation between trans fatty acid intake and depressive symptoms was not affected by the use of antidepressants. In summary, eating more trans fatty acids may be related to increased depressive symptoms in postmenopausal women but not in early perimenopausal ladies.
[NPID: postmenopause, perimenopause, trans fatty acids, diet, depression, midlife]

Year: 2020

Reference: Li, D., Tong, Y., & Li, Y. (2020). Associations of dietary trans fatty acid intake with depressive symptoms in midlife women. Journal of affective disorders, 260, 194–199. https://doi.org/10.1016/j.jad.2019.09.008