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Association between dietary index for gut microbiota and self-reported severe headache or migraine in U.S. adults: a cross-sectional study from NHANES
The diet–microbiota–gut–brain axis is a growing area of research in brain health, with dietary strategies aimed at modifying gut microbiota showing promise for potential benefits. This study by Liu et al. (2025) examined the relationship between the prevalence of severe headaches or migraines in adult Americans and the recently implemented Dietary Index for Gut Microbiota (DI-GM). This cross-sectional study examined data from the National Health and Nutrition Examination Survey (NHANES, 1999–2004), and participants self-reported whether they had experienced severe headaches or migraines in the preceding three months. Dietary recall information was used to compute Dietary Index for Gut Microbiota (DI-GM) scores. After controlling for confounding factors, higher DI-GM and BGMS scores were linked to a lower prevalence of severe headaches or migraines. Furthermore, individuals with a DI-GM score of 4 or higher had a significantly lower risk of experiencing severe headaches or migraines, while no association was found in those with scores below 4. In U.S. adults, a higher DI-GM score was linked to a lower chance of having severe headaches or migraines, especially when scores were higher than 4. [NPID: Cross-sectional study, dietary index for gut microbiota, DI-GM, headache, migraine, NHANES]
Year: 2025
