Assessing the association of coffee consumption on the relationship of chronic pain with depression and anxiety

A bidirectional link between chronic pain (CP) and mental health disorders has been established, with coffee believed to play a role in both areas. However, the specific relationship between coffee and this connection is still unclear. This study by Qin et al. (2024) aims to examine how coffee consumption influences the relationship between chronic pain (CP) and conditions like depression and anxiety. The authors analyzed data from 376,813 participants in the UK Biobank, gathering information on anxiety, depression, and CP. The impact of coffee consumption on the relationship between chronic pain and these mental health conditions was evaluated using logistic and linear regression models. Data analysis indicated significant interactions between coffee consumption and the relationship of CP with depression and anxiety. For instance, the impact of multisite chronic pain (MCP) on self-reported depression was significantly reduced in coffee drinkers compared to non-coffee drinkers. Similarly, the association of MCP with generalized anxiety disorder-7 (GAD-7) scores also differed significantly, following the same trend. When analyzed by gender, the authors observed significant differences in the association between headache and hip pain with self-reported depression among coffee drinkers, where the relationship between headache and hip pain with depression was significantly stronger in male coffee consumers compared to females. The authors conclude that their results indicate how coffee consumption has a significant effect on the relationship between chronic pain and mental health issues such as depression and anxiety. [NPID: Coffee, chronic pain, depression, anxiety]

Year: 2024

Reference: Qin, X., Li, C., Wei, W., He, D., Zhao, Y., Cai, Q., Zhang, N., Chu, X., Shi, S., & Zhang, F. (2024). Assessing the association of coffee consumption on the relationship of chronic pain with depression and anxiety. Nutritional Neuroscience, 27(3), 196–206. https://doi.org/10.1080/1028415X.2023.2175412