Longevity Diet

The Longevity Diet is a dietary framework developed by biogerontologist Valter Longo and colleagues, designed to promote healthy aging, extend healthspan, and reduce the risk of age-related diseases such as cardiovascular disease, type 2 diabetes, cancer, and neurodegeneration.

Grounded in research on nutrient-sensing pathways (including IGF-1, mTOR, and AMPK) and studies of long-lived populations (“Blue Zones”), the framework emphasizes a predominantly plant-based, pescatarian pattern rich in vegetables, legumes, whole grains, nuts, olive oil, and fish; low in animal protein, sugar, and refined carbohydrates; and adjusted in protein intake by age. It also incorporates time-restricted eating within an 11–12-hour daily window and, in some applications, periodic use of a fasting-mimicking diet intended to trigger cellular repair processes such as autophagy.