Gut hormones in microbiota-gut-brain cross-talk

This 2020 review explains the influential role of gut microbiota in the gut-brain axis, focusing on the regulation of physiological functions by the microbiota-related gut hormones. These gut hormones are signalling molecules released by enteroendocrine cells present all over the gastrointestinal tract, and can play a crucial part in maintaining health. The gut microbiota itself are essential in the modulation of several gut-brain axis-related diseases, ranging from gastrointestinal disorders to psychiatric diseases. Sun et al. (2020) encouraged future studies to utilize this microbiota-hormones-gut brain axis in the development of novel therapeutics for psychiatric and gastrointestinal disorders, such as obesity, anxiety, and depression. [NPID: microbiome, MGBA, gut-brain axis, gut microbiome, GI tract, psychiatric diseases, obesity, anxiety, depression]

Year: 2020

Reference: Sun, L. J., Li, J. N., & Nie, Y. Z. (2020). Gut hormones in microbiota-gut-brain cross-talk. Chinese medical journal, 133(7), 826–833. https://doi.org/10.1097/CM9.0000000000000706

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